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Fractional Exhaled Nitric Oxide Among Cement Factory Workers: A Cross Sectional Study.

Tungu, A. M., Bråtveit, M., Mamuya, S. D. and Moen, B. E. (2012) Fractional Exhaled Nitric Oxide Among Cement Factory Workers: A Cross Sectional Study. Occupational and environmental medicine. ISSN 1351-0711

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Abstract

It has been suggested that dust exposure causes airway inflammation among cement factory workers. However, there is limited information on the mechanisms of this effect. We explored any associations between total dust exposure and fractional exhaled nitric oxide (FENO) as a marker of airway eosinophilic inflammation among cement production workers in Tanzania. We also examined possible differences in FENO concentration between workers in different parts of the production line. We examined 127 cement workers and 28 controls from a mineral water factory. An electrochemistry-based NIOX MINO device was used to examine FENO concentration. Personal total dust was collected from the breathing zone of the study participants using 37 mm cellulose acetate filters placed in three-piece plastic cassettes. Interviews on workers' background information were conducted in the Swahili language. RESULTS: We found equal concentrations of FENO among exposed workers and controls (geometric mean (GM)=16 ppb). The GM for total dust among the exposed workers and controls was 5.0 and 0.6 mg/m(3), respectively. The FENO concentrations did not differ between the exposed workers with high (GM≥5 mg/m(3)) and low (GM<5 mg/m(3)) total dust exposure. There was no significant difference in FENO concentration between workers in the two main stages of the cement production process. We did not find any difference in FENO concentration between dust-exposed cement workers and controls, and there were similar FENO concentrations among workers in the two main stages of cement production.

Item Type: Article
Keywords: Fractional Exhaled Nitric Oxide;Cement Factory;Tanzania
Subjects: Health Systems > Community Health
Divisions: Other
Related URLs:
Depositing User: Mr Joseph Madata
Date Deposited: 15 Jan 2013 08:14
Last Modified: 15 Jan 2013 08:14
URI: http://ihi.eprints.org/id/eprint/1032

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