ehealth digital library

Digital library of
the Tanzania
health
community

Prevalence of Wuchereria Bancrofti Antigenemia and Associated Factors Among Children of School Age Born After Initiation of Mass Drug Administration with ivermectin and albendazole in Rufiji district, Tanzania

Clarer, J. (2012) Prevalence of Wuchereria Bancrofti Antigenemia and Associated Factors Among Children of School Age Born After Initiation of Mass Drug Administration with ivermectin and albendazole in Rufiji district, Tanzania. Masters thesis, Muhimbili University of Health and Allied Sciences.

[img]
Preview
PDF
Jones_Clarer.pdf - Other
Available under License Creative Commons Attribution Non-commercial.

Download (721kB)

Abstract

The National Lymphatic Filariasis (LF) Elimination Programme use Ivermectin and Albendazole mass drug administration (MDA) for the control of LF. Screening children of school age has successfully been used for mapping geographical distribution of LF worldwide. The implementation of MDA for LF in Rufiji district started in 2002 and up to 2011, nine rounds had been administered. The prevalence of LF after MDA was not known, thus this study aimed to screen children born during the period of programme implementation in order to assess the transmission status. This study aimed to determine the prevalence of Wuchereria bancrofti antigenaemia and associated factors among school age children born after the initiation of mass drug administration in Rufiji District. A descriptive cross sectional study involving heads of household and school age children born during the implementation of the MDA program was carried out in Rufiji district. Blood samples were drawn from 413 standard one pupils. CFA was tested from the blood sample by using ICT cards in order to establish prevalence of W.bancrofti. A total of 270 heads of household were interviewed so as to establish the relationship between coverage, knowledge and prevalence of bancroftian filariasis. A total of 413 children between the age of 6 and 9 years were tested for CFA, 59 (14.3%) being positive for Wuchereria bancrofti. Two thirds (66.8%) of the children did not take ivermectin and albendazole during the 2011 MDA. Prevalence of Wuchereria bancrofti was lower in younger children (6.4%) than older ones (40.4%). Prevalence of Wuchereria bancrofti was significantly high (70.8%) in children who did not swallow tablets than in those who swallowed the tablets (29.2%), (P = 0.015). Though the larger majority of households (97.0%) had heard of the disease, only 57.0% knew it was transmitted by mosquitoes, while 56.4% had no adequate knowledge on the disease and proper use of drugs. The study also found out that respondents have different cultural beliefs on the cause of the disease and there was improper drug distribution during MDA. The prevalence of Wuchereria bancrofti in Rufiji is still high despite the ongoing elimination programme. Poor knowledge on the disease transmission, cultural beliefs and improper drug distribution were associated with the sustained high prevalence.

Item Type: Thesis (Masters)
Keywords: Wuchereria Bancrofti Antigenemia, Mass Drug Administration, Ivermectin and Albendazole, Rufiji District, Tanzania
Subjects: Health Systems > Surveillance, monitoring & evaluation
Health Systems > Drugs, Medical Supplies & Logistics
Divisions: Muhimbili University of Health and Allied Sciences (MUHAS)
Depositing User: Mr Joseph Madata
Date Deposited: 24 Jul 2013 08:55
Last Modified: 24 Jul 2013 08:55
URI: http://ihi.eprints.org/id/eprint/1720

Actions (login required)

Edit Item Edit Item

Downloads

Downloads per month over past year

View more statistics