ehealth digital library

Digital library of
the Tanzania
health
community

Treatment of Trichomoniasis in Pregnancy in Sub-Saharan Africa Does Not Appear to be Associated with Low Birth Weight or Preterm Birth.

Stringer, E., Read, J. S., Hoffman, I., Valentine, M., Aboud, S. and Goldenberg, R. L. (2010) Treatment of Trichomoniasis in Pregnancy in Sub-Saharan Africa Does Not Appear to be Associated with Low Birth Weight or Preterm Birth. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 100 (1). pp. 58-64. ISSN 0256-9574

[img]
Preview
PDF
Elizabeth_Stringer.pdf - Published Version
Available under License Creative Commons Attribution Non-commercial.

Download (337kB)

Abstract

To determine whether treatment of trichomoniasis increases the risk of prematurity. Sub-analysis of a randomised trial. We analysed data from HPTN trial of antenatal and intrapartum antibiotics to reduce chorioamnionitis-related perinatal HIV transmission. Pregnant women from four sites in Africa. Gestational age at the time of delivery or mean birth weight. Of 2,428 women-infant pairs included, 428 (18%) had trichomoniasis at enrolment. There were no differences in infant age or birth weight between women with or without trichomoniasis. By randomisation group, there were no differences in gestational age at birth or birth weight. Of the 428 women diagnosed with trichomoniasis, 365 (83%) received antibiotics and 63 (15%) did not. In analysis of actual use of antibiotics, women with trichomoniasis who received no treatment were more likely to deliver a preterm infant when the symphysis-fundal height was used to estimate gestational age (36% v. 23%; p=0.03), but not when the Ballard score was used (16% v. 21%; p=0.41). There were no differences in mean birth weight between groups. In pregnant women in sub-Saharan Africa, most of whom were HIV-infected, neither trichomoniasis nor its treatment appears to influence the risk of preterm birth or a low-birth-weight infant.

Item Type: Article
Keywords: Treatment, Trichomoniasis in Pregnancy, Africa, Low Birth Weight, Preterm Birth
Subjects: HIV > PMTCT (prevention of mother-to-child transmission)
Maternal & Neonatal Health > Neonatal Health
Divisions: Other
Depositing User: Mr Joseph Madata
Date Deposited: 16 Mar 2015 08:34
Last Modified: 16 Mar 2015 08:34
URI: http://ihi.eprints.org/id/eprint/1728

Actions (login required)

Edit Item Edit Item

Downloads

Downloads per month over past year

View more statistics