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Artemether-Lumefantrine Treatment Failure despite adequate lumefantrine day 7 Concentration in a Traveller with Plasmodium Falciparum Malaria after Returning from Tanzania.

Färnert, A., Ursing, J., Tolfvenstam, T., Rono, J., Karlsson, L., Sparrelid, E. and Lindegårdh, N. Artemether-Lumefantrine Treatment Failure despite adequate lumefantrine day 7 Concentration in a Traveller with Plasmodium Falciparum Malaria after Returning from Tanzania. Journal of Malaria, 11. p. 176.

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Abstract

Artemether-lumefantrine is currently first-line therapy of Plasmodium falciparum malaria in many countries. This report describes a treatment failure despite adequate drug concentrations in a traveller returning from sub-Saharan Africa. Genotyping confirmed recrudescence and suggested reduced sensitivity. Potential sub-optimal effect of artemether-lumefantrine highlights the need to follow non-immune individuals the weeks after treatment.

Item Type: Article
Keywords: Malaria, P. falciparum, Artemisinin, Lumefantrine, Sensitivity, non-immune
Subjects: Malaria > Diagnosis & treatment
Depositing User: Mr Joseph Madata
Date Deposited: 23 Oct 2013 07:36
Last Modified: 23 Oct 2013 07:36
URI: http://ihi.eprints.org/id/eprint/2218

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