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Aetiology, Antimicrobial Susceptibility and Predictors of Urinary Tract Infection among Febrile Under-Fives at Muhimbili National Hospital, Dar es Salaam-Tanzania

Fredrick, F. , Francis, J. M. , Fataki, M. and Maselle, S. Y. (2013) Aetiology, Antimicrobial Susceptibility and Predictors of Urinary Tract Infection among Febrile Under-Fives at Muhimbili National Hospital, Dar es Salaam-Tanzania. African Journal of Microbiology Research, 7 (12). ISSN 1996-0808

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Abstract

Urinary tract infection (UTI) is a common cause of fever in children and contributes to morbidity and mortality. This study aimed at determining prevalence, aetiology and antimicrobial susceptibility pattern of the isolates at Muhimbili National Hospital (MNH), Dar es Salaam- Tanzania. Demographic data were collected using a pretested questionnaire. 382 febrile children below five years admitted in the general paediatric wards were recruited. Urine specimens were obtained for urinalysis, culture and antimicrobial sensitivity testing. UTI was detected in 16.8% (64/382). Children who presented prolonged duration of fever (7 days or longer) were more likely to have UTI (p< 0.01). Duration of fever, positive leukocyte and nitrite tests were independent predictors of UTI. Isolated bacteria included Escherichia coli (39.1%), Klebsiella spp (31.2%), Staphylococcus epidermidis (6.2%), Staphylococcus aureus (4.7%) and Pseudomonas aeruginosa (4.7%). We observed high resistance of the isolated uropathogens to ampicillin (79.9%), co-trimoxazole (89%) and clavulanate-amoxillin (70.3%). Amikacin had the least resistance (12.5%) from the isolated pathogens.

Item Type: Article
Keywords: Urinary tract infection, uropathogens, antimicrobial susceptibility, UTI, morbidity, mortality, MUhimbili
Subjects: Emerging and Re-emerging Infectious Diseases
Divisions: Muhimbili University of Health and Allied Sciences (MUHAS)
Depositing User: Mr Joseph Madata
Date Deposited: 12 Dec 2013 09:38
Last Modified: 12 Dec 2013 09:38
URI: http://ihi.eprints.org/id/eprint/2351

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