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Larvicidal Efficacy of Cryptomeria Japonica Leaf Essential Oils Against Anopheles gambiae.

Mdoe, F. P., Cheng, S.-S., Lyaruu, L., Nkwengulila, G., Chang, S.-T. and Kweka, E. J. (2014) Larvicidal Efficacy of Cryptomeria Japonica Leaf Essential Oils Against Anopheles gambiae. Parasites & vectors, 7 (1). p. 426. ISSN 1756-3305

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Alternative insecticidal compounds with mortality effect against mosquito life cycle stages are currently needed. The compounds should be biodegradable and nontoxic to non-targeted insects. Plant based larvicides provide effective control of vector populations. This study explored Cryptomeria japonica leaf essential oil larvicidal potency against Anopheles gambiae sensu stricto.
Essential oils (12.5 to 200 mug/mL) extracted from C. japonica leaves were evaluated against An. gambiae s.s. larvae in both the laboratory and semi field in 6 replicates for each dose. Larval mortality readings were taken at 12, 24, 48, and 72 h post treatment. C. japonica leaf essential oil yield was 17.06 +/- 0.56 mL/kg and 1.60 +/- 0.33% (w/w). GC-FID and GC-MS analyses revealed 22 constituents. Essential oil was more effective against An. gambiae s.s. larvae in the laboratory than in semi field trials. Mortality increased with increasing dosages (12.5 to 200 mug/mL) in the laboratory (31.75 to 100%) and semi field trials (17.75 to 99.5%), respectively. The LC50 value ranged from 5.55 to 63.92 mug/mL in the laboratory, and 8.22 to 134.84 mug/mL in semi field conditions, LC90 value ranged from 41.34 to 205.93 mug/mL in the laboratory and 50.92 to 213.11 mug/mL in semi field conditions. This study has demonstrated the potential of C. japonica leaf essential oil to cause mortality effects to An. gambiae s. s. larval populations, however, further studies need to be conducted under field conditions and also with individual active compounds of C. japonica essential oil.

Item Type: Article
Keywords: Cryptomeria japonica, Larvicidal efficacy, Anopheles gambiae s.s, Mortality, Essential oil
Subjects: Malaria > Vector control
Divisions: Catholic University of Health and Allied Sciences (CUHAS)
Depositing User: Mr Joseph Madata
Date Deposited: 15 Sep 2014 06:01
Last Modified: 15 Sep 2014 06:01

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