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Trisomy 21, A Consequence of Advanced Maternal Age

Elisha, O. O. (2012) Trisomy 21, A Consequence of Advanced Maternal Age. Dar es Salaam Medical Journal, 19 (1). pp. 5-6. ISSN 0856-7212

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Abstract

K.M, a 1 year and 9 month old male child from Mwanza was referred from Bugando Hospital to Muhimbili National hospital for further investigations and management. He presented with gradual onset of dry recurrent cough and difficulty in breathing for 20 months and low grade
recurrent fever for 9 months. His mother was 43 years and father 45 years old. On examination he was alert, febrile (38.5oC), acyanotic, with up-slanting eyes, low set ears, flat nose-bridge, small chin, short neck, pigeon chest and webbed toes. He was malnourished with delayed developmental milestones. A pansystolic murmur was auscultated at the lower left sternal edge; and he had impaired speech, reduced muscle bulk and muscle tone with muscle power of grade 3.

Item Type: Article
Keywords: Down's syndrome, Trisomy 21, Chromosome 21, Organ systems, Mental retardation, Hand anomalies, Congenital heart disease
Subjects: ?? MNH2 ??
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Divisions: ?? muhas ??
Depositing User: Users 61 not found.
Date Deposited: 16 Feb 2015 07:04
Last Modified: 16 Feb 2015 07:04
URI: http://ihi.eprints.org/id/eprint/3097

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