ehealth digital library

Digital library of
the Tanzania
health
community

Bacteraemia in Sickle Cell anaemia is Associated with Low Haemoglobin: A Report of 890 Admissions to a Tertiary Hospital in Tanzania.

Makani, J., Mgaya, J., Balandya, E., Msami, K., Soka, D., Cox, S. E., Komba, A. N., Rwezaula, S., Meda, E., Muturi, D., Kitundu, J., Fegan, G., Kirkham, F. J., Newton, C. R., Snow, R. W. and Lowe, B. (2015) Bacteraemia in Sickle Cell anaemia is Associated with Low Haemoglobin: A Report of 890 Admissions to a Tertiary Hospital in Tanzania. British journal of haematology. ISSN 1365-2141

[img]
Preview
PDF
Julie Makani.pdf - Published Version
Available under License Creative Commons Attribution Non-commercial.

Download (72kB) | Preview

Abstract

Bacteraemia is a leading cause of morbidity in sickle cell anaemia (SCA), but information from studies in Africa is limited. We evaluated 890 admissions from 648 SCA patients at a tertiary hospital in Tanzania. Bacteraemia was present in 43 admissions (4·8%); isolates included Staphylococcus aureus (12/43; 28%), non-Typhi Salmonella (9/43; 21%), Streptococcus pneumoniae (3/43; 7%) and Salmonella Typhi (2/43; 5%). Compared to SCA patients without bacteraemia, SCA patients with bacteraemia had significantly lower haemoglobin [71 g/l vs. 62 g/l, odds ratio 0·72 (95% confidence interval 0·56-0·91), P < 0·01]. Further exploration is needed of the relationship between anaemia and bacterial infections in SCA in Africa.

Item Type: Article
Keywords: Bacteraemia, Sickle cell anaemia, Haemoglobin, Admission, Africa
Subjects: Health Systems > Surveillance, monitoring & evaluation
Divisions: Muhimbili University of Health and Allied Sciences (MUHAS)
Depositing User: Mr Joseph Madata
Date Deposited: 30 Jun 2016 06:51
Last Modified: 30 Jun 2016 06:51
URI: http://ihi.eprints.org/id/eprint/3856

Actions (login required)

Edit Item Edit Item

Downloads

Downloads per month over past year

View more statistics