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Breastfeeding and Maternal HIV-1 Disease Progression and Mortality

Sedgh, G., Spiegelman, D.,C., Larsen, U., Msamanga, G. and Fawzi, W. W.,D. Breastfeeding and Maternal HIV-1 Disease Progression and Mortality. AIDS:Official Journal of the International AIDS Society, 18 (7). pp. 1043-1049. ISSN 1473-5571

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Abstract

Objective: To examine the association between breastfeeding and disease progression among HIV-infected women in Dar es Salaam, Tanzania.Design and methods: Cohort study design with Cox proportional hazards models.Results: The relative risk of death comparing women who recently had been breastfeeding to those who were not breastfeeding was 0.47 (95% confidence interval, 0.18-1.20). Neither breastfeeding status nor the duration of exclusive or partial breastfeeding was associated with HIV-1 disease progression, represented by death or development of a low CD4 cell count, anemia or excessive weight loss, in multivariate analyses. These associations remained insignificant when women with relatively low and high CD4 cell counts were analyzed separately.Conclusion: There is insufficient evidence to support the hypothesis that breastfeeding is detrimental to the health of HIV-infected women.

Item Type: Article
Keywords: Breastfeeding, Maternal, HIV-1, Disease Progression,Mortality, Women, Dar es Salaam
Subjects: HIV > PMTCT (prevention of mother-to-child transmission)
Divisions: Other
Depositing User: Mr Joseph Madata
Date Deposited: 11 Sep 2012 06:37
Last Modified: 11 Sep 2012 06:37
URI: http://ihi.eprints.org/id/eprint/403

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